Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell
Caenorhabditis elegans neurons under stress can produce giant vesicles, several microns in diameter, called exophers.Current models suggest that exophers are neuroprotective, providing a mechanism for stressed neurons to eject toxic protein aggregates and organelles.However, little is known of the fate of the exopher once it leaves the neuron.We fo